Micelle promoted multicomponent synthesis of 3-amino alkylated indoles via Mannich-type reaction in water
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Kumar, Atul
Gupta, M K Kumar, Mukesh Saxena, Deepti |
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| Date |
2013-10-17T11:27:43Z
2013-10-17T11:27:43Z 2013 |
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| Identifier |
RSC Advances, 2013, 3, 1673-1678
http://hdl.handle.net/123456789/1149 |
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| Description |
An efficient micelle promoted one-pot synthesis of 3-amino alkylated indoles have been developed via three-component Mannich-type reaction from secondary amines, aldehydes and indoles in water under mild reaction conditions. In this Mannich-type reaction, micelle stabilizes iminium ion which undergoes nucleophilic addition of indole to give 3-amino alkylated indoles in very good yields.
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| Format |
373030 bytes
application/pdf |
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| Language |
en
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| Relation |
CSIR-CDRI Commnication No. 8363
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| Subject |
Micelle
Multicomponent synthesis Mannich Nucleophilic |
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| Title |
Micelle promoted multicomponent synthesis of 3-amino alkylated indoles via Mannich-type reaction in water
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| Type |
Article
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