Studies on Molecular Mechanisms Associated with Narcotic Addiction
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
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| Title |
Studies on Molecular Mechanisms Associated with Narcotic Addiction
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| Creator |
Pal, Ayantika
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| Subject |
Cell Biology & Physiology
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| Description |
The term addiction is used in many contexts to describe an obsession, compulsion or excessive psychological dependence. Addiction is the state of being enslaved to a habit or practice or to something that is psychologically or physically habit-forming, to such an extent
that its cessation causes severe psychological or physical discomfort. According to definition by the Diagnostic and statistical manual of mental disorders, 4th edn. [DSM-IV-TR], American Psychiatric Association (1994), addiction is assumed to be identical to the syndrome of substance dependence. Nestler, the pioneer of work on addiction, defines addiction as a “complex phenomenon with important psychological and social causes and consequences’ [Nestler and Aghajanian, 1997]. According to the definition related to the use of opioids for the treatment of pain, jointly issued by ‘The American Academy of Pain Medicine, the American Pain Society, and the American Society of Addiction Medicine in 2001’, addiction is a “neurobiological, compulsive disorder in which an individual becomes preoccupied with obtaining and using a substance-- and experiences a lack of control over
using that substance -- despite continued use that results in a decreased quality of life and significant adverse consequences.” Addiction can be broadly classified into two major forms, namely substance and process. Substance addiction constitutes addiction to substances or drugs like nicotine, alcohol, opioids, stimulants etc. Process or behavioural addiction occurs where a person is repeatedly
engaged to a typical activity, like video game, work, computer, shopping, gambling, social networking, etc. It is increasingly clear from recent studies that many of these behavioural addiction phenomenons in individuals have similar symptoms of substances addiction and undergo the same consequences brought about by addiction to alcohol and drugs. Surprisingly, “non-substance related behavioral addiction” was not listed in either of the two
internationally used diagnostic manuals of mental disorders, DSM-IV-TR and International Classification of Disease.
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| Date |
2013-12-26
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| Type |
Thesis
NonPeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/2128/1/thesis%2Dayantika.pdf
Pal, Ayantika (2013) Studies on Molecular Mechanisms Associated with Narcotic Addiction. PhD thesis, CU. |
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| Relation |
http://www.eprints.iicb.res.in/2128/
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