Porous Polyurea Network Showing Aggregation Induced White Light Emission, Applications as Biosensor and Scaffold for Drug Delivery
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Porous Polyurea Network Showing Aggregation Induced White Light Emission, Applications as Biosensor and Scaffold for Drug Delivery
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| Creator |
Bhunia, Subhajit
Chatterjee, Nabanita Das, Subhadip Das Saha, Krishna Bhaumik, Asim |
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| Subject |
Cancer Biology and Inflammatory Disorder Division
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| Description |
We have designed a urea functionalized novel nanoporous material, POP-PU, which showsaggregation induced white light emission in the presence of suitable polar solvents. This nanomaterial has been explored as a pseudowhite light
emitter where the polymeric luminogen moiety can interact with the suitable polar solvent, leading to charge transfer. Thus, solvent assisted rotational freezing of
nonrigid polymeric nanoparticles gives radiative emission and the whole solution emits white light with color temperature of 8533 K. This nanoporous material also
holds the pockets (donor−donor−acceptor array) for specific biomolecular interaction. Among three pyrimidine based nucleotide bases, only cytosine can amplify the PL emission intensity of POP-PU and the other two bases cannot,
suggesting its future potential as a biosensor. Further, this urea functionalized porous organic nanomaterial can be utilized as an efficient drug-delivery vehicle for
liver cancer diagnostics and therapy based on the specific biomolecular interaction at its surface.
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| Date |
2014
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/2132/1/ACS_APPLIED_MATERIALS_%26_INTERFACES___6_(_24);2014.pdf
Bhunia, Subhajit and Chatterjee, Nabanita and Das, Subhadip and Das Saha, Krishna and Bhaumik, Asim (2014) Porous Polyurea Network Showing Aggregation Induced White Light Emission, Applications as Biosensor and Scaffold for Drug Delivery. ACS Applied Materials & Interfaccs, 6 (24). pp. 22569-22576. |
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| Relation |
http://dx.doi.org/10.1021/am5066859 | ACS Appl
http://www.eprints.iicb.res.in/2132/ |
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