AN ATP-Independent Catenating Enzyme from the Kinetoplast Hemoflagellate Leishmania donovani
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
AN ATP-Independent Catenating Enzyme from the Kinetoplast
Hemoflagellate Leishmania donovani
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| Creator |
Chakraborty, A K
Majumder, Hemanta K |
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| Subject |
Infectious Diseases and Immunology
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| Description |
An enzyme from Leishmania donovani that catenates monomeric
pBR322 into huge catenanes has been isolated and characterized. The enzyme also decatenates kinetoplast DNA networks into covalently closed monomeric circles and relaxes supercoiled pBR322. The catenatlon, decatenation and relaxation reactions do not require ATP. The formation
of topological isomers of unique linking numbers suggest that the enzyme is a type II DNA topoisomerase
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| Publisher |
Elsevier
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| Date |
1991
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/2283/1/BIOCHEMICAL_AND_BIOPHYSICAL_RESEARCH_COMMUNICATIONS__V._180_(_1__)_279%2D285;1991.pdf
Chakraborty, A K and Majumder, Hemanta K (1991) AN ATP-Independent Catenating Enzyme from the Kinetoplast Hemoflagellate Leishmania donovani. Biochemical and Biophysical Research Communications, 180 (1). pp. 279-285. |
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| Relation |
http://www.eprints.iicb.res.in/2283/
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