Nonlinearity in the I-V characteristics in thin lipid films Effect of AC and DC fields
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Nonlinearity in the I-V characteristics in thin lipid films
Effect of AC and DC fields
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| Creator |
Bhattacharyya, D
Basu, R Ghosh, A Manna, A Nandy, A Nandy, P |
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| Subject |
Structural Biology & Bioinformatics
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| Description |
The current-voltage characteristics of bilayer lipid membranes of oxidized cholesterol separating two bathing solutions have already been extensively studied under a DC electric field. The observed deviation from linearity at high field has been explained by field-induced pore formation, which then act as ion channels in the membrane. Using thin films of oxidized cholesterol and of dipalmitoyl
phosphatidylcholine, we have reported for the first time similar deviation from nonlinearity in the DC I-V characteristics when the applied field is above 40 V/cm. Upon application of an AC field, the conductivity increases as square of frequency, while the nonlinear nature of
the I-V characteristic curve is still retained at all frequencies up to 5,000 Hz. Our results indicate that besides pore formation, the intrinsic electrical properties of the constituent lipid molecules are also responsible for the observed nonlinearity.
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| Publisher |
Biophysical Society
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| Date |
1993
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/2312/1/BIOPHYSICAL_JOURNAL__V.__(_2_)_550%2D552;1993[55].pdf
Bhattacharyya, D and Basu, R and Ghosh, A and Manna, A and Nandy, A and Nandy, P (1993) Nonlinearity in the I-V characteristics in thin lipid films Effect of AC and DC fields. Biophysical Journal, 2. pp. 550-552. ISSN 0006-3495 |
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| Relation |
http://www.eprints.iicb.res.in/2312/
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