Role and regulation of RNA helicase p68 in cancer
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Role and regulation of RNA helicase p68 in cancer
|
|
| Creator |
Sarkar, Moumita
|
|
| Subject |
Cancer Biology and Inflammatory Disorder Division
|
|
| Description |
Cancer is one of the leading causes of mortality despite significant advances in therapy and
diagnosis. Colorectal cancer ranks the fourth most common cause of morbidity worldwide. It
accounts for over 9% of all cancer incidences. It is the second most preventable cancer if
diagnosed early. For homeostasis of an organism, cell responds to various signaling cues to
regulate gene expression. Specific stimuli initiate a signaling cascade by binding to cell surface
receptors which convey the signal via several kinase and phosphatase proteins to downstream
transcription factors which ultimately leads to up or downregulation of specific genes. Aberrant
signaling networks deregulate gene expression profile, leading to cancer. Transcriptional
regulation attributes a major control on gene expression
|
|
| Date |
2015
|
|
| Type |
Thesis
NonPeerReviewed |
|
| Format |
application/pdf
|
|
| Identifier |
http://www.eprints.iicb.res.in/2331/1/Thesis_Moumita_Sarkar_2015.pdf
Sarkar, Moumita (2015) Role and regulation of RNA helicase p68 in cancer. PhD thesis, CU. |
|
| Relation |
http://www.eprints.iicb.res.in/2331/
|
|