Synthetic Studies on Fused N-/O-Based Heterocycles and Sugar Containing Heterocyclic Molecules of Biological Importance
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
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Title |
Synthetic Studies on Fused N-/O-Based Heterocycles and Sugar Containing Heterocyclic Molecules of Biological Importance
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Creator |
Chatterjee, Nivedita
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Subject |
Chemistry
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Description |
Chapter I. This chapter is sub-divided into 4 parts.
Part A contains a brief review of the metal mediated coupling reactions for the synthesis of N-/O-rich heterocycles mainly by Sonogashira cyclization reactions. The recent modifications of Sonogashira cyclization reactions are also included in this part.
Part B. In this section green approach for the regio- & stereo-selective syntheses of Z)-3-methyleneisoindoline-1-ones in aqueous medium has been described. The introduction to the work, results and discussion, experimental procedures, conclusion, spectroscopic data and related references are also included. The work has been published
in Tetrahedron Lett. 2013, 54, 3748-3751.
Part C contains the synthesis of 3-alkyl/aryl-3-(pyrrole-2-yl)-2-phenyl-2,3-dihydroisoindolinones and 3-alkyl/aryl-3-(indole-3-yl)-2-phenyl-2,3-dihydro-isoindolinones using
nanodomain cubic cuprous oxide as reusable catalyst in aqueous medium under one-pot condition. The introduction to the work, results and discussion, experimental procedures,
conclusion, spectroscopic data and related references are included. The work has been published in RSC Adv., 2014, 4, 7024-7029.
Part D deals with regio- and stereo- selective syntheses of (Z)-3-methyleneisoindoline- 1-ones and furo[3,2-h]quinolines using reusable palladium nanoparticles in onepot domino Sonogashira-cyclization in aqueous medium. The introduction, results and discussion, experimental procedures, conclusion, spectroscopic data and related references are included. The work has been communicated to Tetrahedron Lett.
Chapter II. This chapter is sub-divided into three parts.
Part A. This part contains a brief review of the syntheses of 1,2,3-triazole linked
glycoconjugates and fused heterocycles. The syntheses of some important biologically active compounds along with related references reported in the literature are also
incorporated.
Part B. Application of nanodomain cubic cuprous oxide as reusable catalyst for the synthesis of triazole-fused tetracyclic glycosides and heterocycles in aqueous medium is
described in this chapter. The introduction to the work, results and discussion, experimental procedures, conclusion, spectroscopic data and related references are included. The work has been published in Tetrahedron Lett. 2015, 56, 3886-3889.
Part C deals with the syntheses of triazolo benzoxazines, triazolo quinoxalines,
triazolo benzodiazepines, triazolo benzoxazepines and triazolo benzthiazines via a simple and convenient protocol using basic alumina as solid support. The introduction to the work, results and discussion, experimental procedures, conclusion, spectroscopic data and related references are included in this part. The work has been published in Tetrahedron Lett. 2014, 55, 2261-2265.
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Date |
2015
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Type |
Thesis
NonPeerReviewed |
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Format |
application/pdf
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Identifier |
http://www.eprints.iicb.res.in/2474/1/Thesis_Nivedita_Chatterjee.pdf
Chatterjee, Nivedita (2015) Synthetic Studies on Fused N-/O-Based Heterocycles and Sugar Containing Heterocyclic Molecules of Biological Importance. PhD thesis, University of Calcutta. |
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Relation |
http://www.eprints.iicb.res.in/2474/
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