Design of a novel microtubule targeted peptide vesicle for delivering different anticancer drugs
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Design of a novel microtubule targeted peptide
vesicle for delivering different anticancer drugs
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| Creator |
Adak, Anindyasundar
Mohapatra, Saswat Mondal, Prasenjit Jana, Batakrishna Ghosh, Surajit |
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| Subject |
Chemistry
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| Description |
A microtubule targeted peptide-based delivery vehicle has been designed using two oppositely charged peptides, which targets tubulin/microtubules, delivers both hydrophilic and hydrophobic drugs into their target site through lysosome at acidic pH. Drug loaded vesicles show a significant anticancer effect compared to control drugs in a 2D monolayer and a 3D spheroid cell.
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| Date |
2016-04-22
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/2622/1/Chem._Commun.%2C_2016.pdf
Adak, Anindyasundar and Mohapatra, Saswat and Mondal, Prasenjit and Jana, Batakrishna and Ghosh, Surajit (2016) Design of a novel microtubule targeted peptide vesicle for delivering different anticancer drugs. Chemical Communication, 52. pp. 7549-7552. |
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| Relation |
http://dx.doi.org/10.1039/c6cc01769j
http://www.eprints.iicb.res.in/2622/ |
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