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Microwave assisted synthesis and antibacterial properties of some new 2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo[2,1-<i style="mso-bidi-font-style: normal">b</i>][1,3,4]thiadiazoles

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Title Microwave assisted synthesis and antibacterial properties of some new 2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo[2,1-<i style="mso-bidi-font-style: normal">b</i>][1,3,4]thiadiazoles
 
Creator Jakhar, Anshu
Makrandi, J K
 
Subject Microwave irradiation
<span style="font-size:10.0pt;font-family: "Times New Roman","serif";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-GB;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-GB">2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo [2,1-<i style="mso-bidi-font-style:normal">b</i>][1,3,4]thiadiazoles</span>
3-(2-bromoacetyl)-6-substitutedcoumarins
5-alkyl/aryl-2-amino-1,3,4-thiadiazoles
Antibacterial properties
 
Description 291-296
A series of 2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo[2,1-<i style="mso-bidi-font-style: normal">b</i>][1,3,4] thiadiazoles <b style="mso-bidi-font-weight:normal">3a-o</b> have been synthesized by reacting 3-(2-bromoacetyl)-6-substitutedcoumarins <b style="mso-bidi-font-weight:normal">1</b> with various 5-alkyl/aryl-2-amino-1,3,4-thiadiazoles <b style="mso-bidi-font-weight:normal">2</b> under normal thermal condition as well as microwave irradiation. The latter condition is found to be much more efficient in terms of time and yield. The structures of the newly synthesized compounds have been characterized by elemental analysis, IR and <sup>1</sup>H NMR spectral data. All the newly synthesized compounds have been tested for their antibacterial properties against gram-positive and gram-negative bacteria.
 
Date 2012-01-14T19:07:39Z
2012-01-14T19:07:39Z
2012-01
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/13405
 
Language en_US
 
Rights <img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
 
Publisher NISCAIR-CSIR, India
 
Source IJC-B Vol.51B(01) [January 2012]