Microwave assisted synthesis and antibacterial properties of some new 2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo[2,1-<i style="mso-bidi-font-style: normal">b</i>][1,3,4]thiadiazoles
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
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Title |
Microwave assisted synthesis and antibacterial properties of some new 2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo[2,1-<i style="mso-bidi-font-style: normal">b</i>][1,3,4]thiadiazoles
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Creator |
Jakhar, Anshu
Makrandi, J K |
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Subject |
Microwave irradiation
<span style="font-size:10.0pt;font-family: "Times New Roman","serif";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-GB;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-GB">2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo [2,1-<i style="mso-bidi-font-style:normal">b</i>][1,3,4]thiadiazoles</span> 3-(2-bromoacetyl)-6-substitutedcoumarins 5-alkyl/aryl-2-amino-1,3,4-thiadiazoles Antibacterial properties |
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Description |
291-296
A series of 2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo[2,1-<i style="mso-bidi-font-style: normal">b</i>][1,3,4] thiadiazoles <b style="mso-bidi-font-weight:normal">3a-o</b> have been synthesized by reacting 3-(2-bromoacetyl)-6-substitutedcoumarins <b style="mso-bidi-font-weight:normal">1</b> with various 5-alkyl/aryl-2-amino-1,3,4-thiadiazoles <b style="mso-bidi-font-weight:normal">2</b> under normal thermal condition as well as microwave irradiation. The latter condition is found to be much more efficient in terms of time and yield. The structures of the newly synthesized compounds have been characterized by elemental analysis, IR and <sup>1</sup>H NMR spectral data. All the newly synthesized compounds have been tested for their antibacterial properties against gram-positive and gram-negative bacteria. |
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Date |
2012-01-14T19:07:39Z
2012-01-14T19:07:39Z 2012-01 |
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Type |
Article
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Identifier |
0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/13405 |
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Language |
en_US
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Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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Publisher |
NISCAIR-CSIR, India
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Source |
IJC-B Vol.51B(01) [January 2012]
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