Bifunctional Luminomagnetic Rare-Earth Nanorods for High-Contrast Bioimaging Nanoprobes
IR@NPL: CSIR-National Physical Laboratory, New Delhi
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| Title |
Bifunctional Luminomagnetic Rare-Earth Nanorods for High-Contrast Bioimaging Nanoprobes
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| Creator |
Gupta, Bipin Kumar
Singh, Satbir Kumar, Pawan Lee, Yean Kedawat, Garima Narayanan, Tharangattu N. Vithayathil, Sajna Antony Ge, Liehui Zhan, Xiaobo Gupta, Sarika Martí, Angel A. Vajtai, Robert Ajayan, Pulickel M. Benny , Abraham Kaipparettu |
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| Subject |
General Science
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| Description |
Nanoparticles exhibiting both magnetic and luminescent properties are need of the hour for many biological applications. A single compound exhibiting this combination of properties is uncommon. Herein, we report a strategy to synthesize a bifunctional luminomagnetic Gd2-xEuxO3 (x = 0.05 to 0.5) nanorod, with a diameter of similar to 20 nm and length in similar to 0.6 mu m, using hydrothermal method. Gd2O3:Eu3+ nanorods have been characterized by studying its structural, optical and magnetic properties. The advantage offered by photoluminescent imaging with Gd2O3:Eu3+ nanorods is that this ultrafine nanorod material exhibits hypersensitive intense red emission (610 nm) with good brightness (quantum yield more than 90%), which is an essential parameter for high-contrast bioimaging, especially for overcoming auto fluorescent background. The utility of luminomagnetic nanorods for biological applications in high-contrast cell imaging capability and cell toxicity to image two human breast cancer cell lines T47D and MDA-MB-231 are also evaluated. Additionally, to understand the significance of shape of the nanostructure, the photoluminescence and paramagnetic characteristic of Gd2O3:Eu3+ nanorods were compared with the spherical nanoparticles of Gd2O3:Eu3+.
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| Publisher |
Nature Publishing Group
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| Date |
2016-09-02
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://npl.csircentral.net/2156/1/Bifunctional%20Luminomagnetic.pdf
Gupta, Bipin Kumar and Singh, Satbir and Kumar, Pawan and Lee, Yean and Kedawat, Garima and Narayanan, Tharangattu N. and Vithayathil, Sajna Antony and Ge, Liehui and Zhan, Xiaobo and Gupta, Sarika and Martí, Angel A. and Vajtai, Robert and Ajayan, Pulickel M. and Benny , Abraham Kaipparettu (2016) Bifunctional Luminomagnetic Rare-Earth Nanorods for High-Contrast Bioimaging Nanoprobes. Scientific Reports, 6. pp. 1-12. ISSN 2045-2322 |
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| Relation |
http://npl.csircentral.net/2156/
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