Molecular Functionalization of Carbon Nanomaterials for Immuno-diagnosis of Cancer
IR@NPL: CSIR-National Physical Laboratory, New Delhi
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| Title |
Molecular Functionalization of Carbon Nanomaterials for Immuno-diagnosis of Cancer
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| Creator |
Singh, Anu
Choudhary, Meenakshi Kaur, Satbir Singh, Surinder P. Arora, Kavita |
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| Subject |
Materials Science
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| Description |
Carbon nanomaterials possess amazing physico-chemical properties with great potential for molecular functionalization to construct sensitive biosensors. We report a study of graphene oxide (GO) and carbon nanotubes (CNTs), to achieve, reusable, low cost and efficient immuno-sensing platform for lung cancer. Presence of biomarker (hTERT) was detected in concentration range of 10 ag mL(-1) -50 ng mL(-1) and 5 fg mL(-1) -50 ng mL(-1) using GO and CNT based nanocomposites, respectively. Subsequently, due to favourable attributes (peak current, stability, repeatability and reproducibility) achieved through CNT, simultaneous bianalyte detection of biomarkers (MAGE A2/A11)) expressed in serum, were demonstrated.
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| Publisher |
Elsevier
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| Date |
2016
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://npl.csircentral.net/2280/1/Molecular%20Functionalization%20of%20Carbon.pdf
Singh, Anu and Choudhary, Meenakshi and Kaur, Satbir and Singh, Surinder P. and Arora, Kavita (2016) Molecular Functionalization of Carbon Nanomaterials for Immuno-diagnosis of Cancer. Materials Today: Proceedings , 3 (2). 157-161 . ISSN 2214-7853 |
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| Relation |
http://npl.csircentral.net/2280/
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