Using Chou's general PseAAC to analyze the evolutionary relationship of receptor associated proteins (RAP) with various folding patterns of protein domains
IR@IMTECH: CSIR-Institute of Microbial Technology, Chandigarh
View Archive Info| Field | Value | |
| Title |
Using Chou's general PseAAC to analyze the evolutionary relationship of receptor associated proteins (RAP) with various folding patterns of protein domains
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| Creator |
Muthu Krishnan, S.
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| Subject |
QR Microbiology
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| Description |
The receptor-associated protein (RAP) is an inhibitor of endocytic receptors that belong to the lipoprotein receptor gene family. In this study, a computational approach was tried to find the evolutionarily related fold of the RAP proteins. Through the structural and sequence-based analysis, found various protein folds that are very close to the RAP folds. Remote homolog datasets were used potentially to develop a different support vector machine (SVM) methods to recognize the homologous RAP fold. This study helps in understanding the relationship of RAP homologs folds based on the structure, function and evolutionary history.
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| Publisher |
Elsevier
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| Date |
2018-05-14
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| Type |
Article
PeerReviewed |
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| Relation |
http://dx.doi.org/10.1016/j.jtbi.2018.02.008
http://crdd.osdd.net/open/2018/ |
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| Identifier |
Muthu Krishnan, S. (2018) Using Chou's general PseAAC to analyze the evolutionary relationship of receptor associated proteins (RAP) with various folding patterns of protein domains. Journal of Theoretical Biology, 445. pp. 62-74. ISSN 00225193
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