An efficient protocol for the one-pot four-component synthesis of 6-amino-1, 4-dihydropyrano[2,3-<em>c</em>]-pyrazole-5-carbonitrile derivatives using starch solution as a reaction media
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
An efficient protocol for the one-pot four-component synthesis of 6-amino-1, 4-dihydropyrano[2,3-<em>c</em>]-pyrazole-5-carbonitrile derivatives using starch solution as a reaction media
|
|
| Creator |
Vekariya, Rajesh H
Patel, Kinjal D Patel, Hitesh D |
|
| Subject |
Pyrano[2,3-<em>c</em>]-pyrazoles
Starch solution One-pot synthesis Multi-component reaction |
|
| Description |
576-582
An efficient, high-yielding and rapid protocol has been developed for the synthesis of 6-amino-1,4-dihydropyrano [2,3-<em>c</em>]pyrazol-5-carbonitrile derivatives through four-component, one-pot cyclocondensation reaction of ethyl acetoacetate, hydrazine hydrate, aldehydes and malononitrile utilizing starch solution as a highly efficient homogenous catalyst. The use of a nontoxic, reusable and biodegradable catalyst is one of the superior advantages of this protocol. Short reaction times, mild conditions, excellent product yields, simple work-up procedure and non use of toxic organic solvents are added advantages of this procedure. |
|
| Date |
2018-04-12T05:40:08Z
2018-04-12T05:40:08Z 2018-04 |
|
| Type |
Article
|
|
| Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/44177 |
|
| Language |
en_US
|
|
| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
|
|
| Publisher |
NISCAIR-CSIR, India
|
|
| Source |
IJC-B Vol.57B(04) [April 2018]
|
|