A new antibacterial imidazole from the marine sponge <em>Iricinia fusca</em>
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
A new antibacterial imidazole from the marine sponge <em>Iricinia fusca</em>
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| Creator |
Meesala, Srinu
Singh, Ruby Watve, Milind G Naik, Dattatraya G. |
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| Subject |
Anticancer activity
Antimicrobial Imidazole alkaloids Mass spectrometry NMR Sponge |
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| Description |
75-78
A new imidazole alkaloid (1) along with two known compounds, variabilin (2) and iricinialactam A (3) have been isolated from the Arabian marine sponge <em>Ircinia fusca.</em> The structure of the new compound was established as 4-((1, 2-dihydroxy-5-(methyl (1-methyl-1H-imidazol-4-yl) amino) pentan-3-yl) oxy)-3, 5-dimethoxy-1-methylpyrrolidin-2-one (1) by 1D and 2D NMR, and high-resolution electrospray ionization mass spectrometry (HRESIMS). Compound 1 exhibited selective growth inhibitory activity against gram-positive bacteria <em>S. aureus</em> at 100 µg/mL. |
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| Date |
2018-07-03T11:57:27Z
2018-07-03T11:57:27Z 2018-03 |
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| Type |
Article
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| Identifier |
0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/44634 |
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| Language |
en_US
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| Relation |
Int. cl. (2015.01)−A01N 63/00, CO7D 403/14
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJNPR Vol.9(1) [March 2018]
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