Evaluation of the haematinic activity of <em>Opuntia elatior</em> Mill. fruit
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Evaluation of the haematinic activity of <em>Opuntia elatior</em> Mill. fruit
|
|
| Creator |
Patel, Hemil
Prajapati, Shashikant Ranade, Anagha Acharya, Rabinarayan Kumar, Nariya Mukesh |
|
| Subject |
Anemia
Haematinic activity Mercuric chloride <i>Nagaphani</i> <em>Opuntia elatior</em> Mill |
|
| Description |
39-46
<em>Opuntia elatior</em>, known as <em>Nagaphani</em> or <em>Hathalo-thore</em> belongs to the family Cactaceae. It is one of the <em>Opuntia</em> species used as medicine for various ailments due to its beneficial health-promoting properties. Fruits of <em>Opuntia elatior</em> have been advocated in anaemia, asthma, cough, inflammation, and gonorrhoea in Gujarat. The present study was planned to evaluate the hematinic effect of <em>Opuntia elatior</em> Mill. fruit on mercuric chloride (HgCl<sub>2</sub>) induced anaemia in rats. <em>Opuntia elatior</em> fruit <em>Swarasa</em> was administered to Charle’s foster albino rats for 30 consecutive days at the doses of 1.8 mL/kg and 3.6 mL/kg. The effects of both drugs were assessed on ponderal changes, haematological, serum biochemical, and histopathology of various organs. The fruit <em>Swarasa</em> showed significant increase in the haemoglobin content, serum ferritin level and serum TIBC level. The test drug at both dose levels produced adverse changes of mild intensity in liver, kidney and heart and reverted the disturbance in the cytoarchitecture of the spleen, thymus and lymph node. Test drug <em>Opuntia elatior</em> fruit <em>Swarasa</em> reversed anaemia induced by HgCl<sub>2</sub> in a dose-dependent manner. The results support the traditional use of fruits in the treatment of anaemia. |
|
| Date |
2018-07-03T12:27:18Z
2018-07-03T12:27:18Z 2018-03 |
|
| Type |
Article
|
|
| Identifier |
0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/44639 |
|
| Language |
en_US
|
|
| Relation |
Int. cl. (2015.01)−A61K 36/00, 36/33
|
|
| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
|
|
| Publisher |
NISCAIR-CSIR, India
|
|
| Source |
IJNPR Vol.9(1) [March 2018]
|
|