Phytochemical screening, antioxidant and antiproliferative activities of successive extracts of <em>Couroupita guianensis</em> Aubl. plant
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Phytochemical screening, antioxidant and antiproliferative activities of successive extracts of <em>Couroupita guianensis</em> Aubl. plant
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| Creator |
Sirisha, M
Jaishree, V |
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| Subject |
DPPH
Hydroxyl radical Lipid peroxidation Nitric oxide free radical Total antioxidant capacity Total phenol content |
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| Description |
22-27
<em>Couroupita guianensis</em> Aubl. is widely used in Indian traditional medicines to treat stomach aches, cold, skin diseases, microbial and fungal infections. In the present study series of experiments were performed to screen phytochemical constituents, antioxidant and antiproliferative activities of successive extracts of leaves, stem and crude methanolic extract of flowers of <em>Couroupita guianensis</em>. The extracts were evaluated for their antioxidant activity by 1,1’-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, nitric oxide free radical scavenging activity, hydrogen peroxide scavenging, lipid peroxide inhibitory activity, hydroxyl radical by deoxyribose method and total antioxidant capacity of extracts and cytotoxic property of extracts as well as total phenolic content. The methanolic leaf extract showed highest total phenol content. Ethyl acetate and methanol extracts were found to possess excellent antioxidant activity in most of the tested methods. In the cytotoxicity study of extracts, the results suggested that ethyl acetate leaf and crude methanolic flower extracts possess better activity. |
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| Date |
2018-07-03T12:38:11Z
2018-07-03T12:38:11Z 2018-03 |
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| Type |
Article
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| Identifier |
0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/44642 |
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| Language |
en_US
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| Relation |
Int. cl. (2015.01)−A61k 36/00
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJNPR Vol.9(1) [March 2018]
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