Synthesis of pyrazolo[4ʹ,3ʹ:5,6]pyrano[2,3-<em>d</em>]pyrimidine derivatives and their antimicrobial, antimalarial and antituberculosis evaluation
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Synthesis of pyrazolo[4ʹ,3ʹ:5,6]pyrano[2,3-<em>d</em>]pyrimidine derivatives and their antimicrobial, antimalarial and antituberculosis evaluation
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| Creator |
Vekariya, Rajesh H
Patel, Kinjal D Vekariya, Mayur K Prajapati, Neelam P Rajani, Dhanji P Rajani, Smita D Patel, Hitesh D |
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| Subject |
Pyrazolo[4,3-<i>d</i>]isoxazol
Isoxazol-5(4<i>H</i>)-ones Green synthesis Antimicrobial Antimalarial Antituberculosis |
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| Description |
997-1005
This article deals with the synthesis of a new pyrazolo[4ʹ,3ʹ:5,6]pyrano[2,3-<em>d</em>]pyrimidine derivatives by the reaction of 1,4-dihydropyrano[2,3-<em>c</em>]-pyrazole-5-carbonitriles with ethyl cyanoacetate catalyzed by triethylamine (TEA) in ethanol under reflux conditions. All the synthesized compounds have been checked for their purity by melting point and TLC, and have been characterized through various spectroscopic techniques such as <sup>1</sup>H and <sup>13</sup>C NMR, IR, ESI-MS and elemental analysis. All synthesized compounds have been screened for antimicrobial, antimalarial and antituberculosis activity. |
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| Date |
2018-07-23T06:25:22Z
2018-07-23T06:25:22Z 2018-07 |
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| Type |
Article
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/44744 |
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| Language |
en_US
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJC-B Vol.57B(07) [July 2018]
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