Synthesis, characterization and antimicrobial activity of some ethyl-2-(4-(2-isonicotinoylhydrazinyl)-6-(arylamino)-1,3,5-triazin-2-ylamino)-4- methylthiazole-5-carboxylates
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Synthesis, characterization and antimicrobial activity of some ethyl-2-(4-(2-isonicotinoylhydrazinyl)-6-(arylamino)-1,3,5-triazin-2-ylamino)-4- methylthiazole-5-carboxylates
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| Creator |
Desai, N C
Makwana, Atul H Senta, R D |
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| Subject |
1,3,5-Triazine
Antimicrobial activity Isoniazid MIC Thiazole |
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| Description |
974-982
In the present study, isoniazid, thiazole and 1,3,5-triazine moieties have been clubbed in one frame work to synthesize a new series of ethyl 2-(4-(2-isonicotinoylhydrazinyl)-6-(arylamino)-1,3,5-triazin-2-ylamino)-4-methylthiazole-5-carboxylates <strong>3a-n</strong>. The newly synthesized compounds have been screened for their <em>in vitro</em> antimicrobial activity. Compounds <strong>3a</strong>, <strong>3c</strong>, <strong>3d</strong> and <strong>3l</strong> have exhibited significant antimicrobial activity on several strains of microbes. The structures of the newly synthesized compounds have been elucidated by IR, <sup>1</sup>H and <sup>13</sup>C NMR, and mass spectral analysis. |
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| Date |
2018-07-23T06:38:48Z
2018-07-23T06:38:48Z 2018-07 |
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| Type |
Article
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/44747 |
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| Language |
en_US
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJC-B Vol.57B(07) [July 2018]
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