One pot multicoponent synthesis of 4-hydroxy-6-methyl-3-(3 phenylthiazolo [2,3<em>c</em>][1,2,4]triazol-5-yl)-2<em>H</em>-pyran-2-ones
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
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| Title |
One pot multicoponent synthesis of 4-hydroxy-6-methyl-3-(3 phenylthiazolo [2,3<em>c</em>][1,2,4]triazol-5-yl)-2<em>H</em>-pyran-2-ones
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| Creator |
Thirupaiah, Bade
Sujatha, Kodam Rao, Vedula Rajeswar |
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| Subject |
Dehydroacetic acid
Benzoic acid Thiosemicarbazide Thiazole Thiazolo triazole Multicomponent reaction |
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| Description |
960-964
An efficient one pot multicomponent reaction for the synthesis of 4-hydroxy-6-methyl-3-(3-phenylthiazolo[2,3-<em>c</em>][1,2,4]triazol-5-yl)-2<em>H</em>-pyran-2-ones with good to excellent yields have been described. Reaction of 3-(2-bromoacetyl)-4-hydroxy-6-methyl-2<em>H</em>-pyran-2-one <strong>1</strong>, thiosemicarbazide <strong>2</strong> and various aromatic carboxylic acids <strong>3a-j</strong> in dry toluene and POCl<sub>3</sub> afford 4-hydroxy-6-methyl-3-(3-phenylthiazolo[2,3-<em>c</em>][1,2,4]triazol-5-yl)-2<em>H</em>-pyran-2-ones. All the synthesized compounds have been characterized from their analytical and spectral data. |
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| Date |
2018-07-23T06:45:50Z
2018-07-23T06:45:50Z 2018-07 |
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| Type |
Article
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/44749 |
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| Language |
en_US
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJC-B Vol.57B(07) [July 2018]
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