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Synthesis and anti-microbial screening of <em>N</em>-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(arylphenyl)acetamide

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Title Synthesis and anti-microbial screening of <em>N</em>-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(arylphenyl)acetamide
 
Creator Shukla, Maharshi B
Mahyavanshi, Jyotindra B
Joshi, Prakash J
 
Subject 2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile
Acetamide
Antifungal activity
Antibacterial activity
 
Description 1222-1227
Reactions of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile with 2-chloro-<em>N</em>-(aryl)-acetamides give <em>N</em>-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(arylphenyl)acetamide. The structure of novel compounds has been established on the basis of their substituted <em>N</em>-chloro aryl acetamide derivatives. All the compounds have been characterized by FT-IR, <sup>1</sup>H NMR and mass spectroscopy. These new compounds have been evaluated for their <em>in vitro</em> antibacterial and antifungal activity.
 
Date 2018-09-13T05:41:01Z
2018-09-13T05:41:01Z
2018-09
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/45040
 
Language en_US
 
Rights <img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
 
Publisher NISCAIR-CSIR, India
 
Source IJC-B Vol.57B(09) [September 2018]