Anti-inflammatory activity and phenolic composition of a traditional medicinal plant from Turkey: <em>Potentilla recta </em>L.
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Anti-inflammatory activity and phenolic composition of a traditional medicinal plant from Turkey: <em>Potentilla recta </em>L.
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| Creator |
Ökdem, Başak
Karatoprak, Gökçe Şeker Koşar, Müberra |
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| Subject |
<i>Potentilla recta</i>
Potentillin LC-MS/MS Anti-inflammatory activity |
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| Description |
691-698
<em>Potentilla recta</em> L. (Rosaceae) is traditionally used for its antibacterial, anti-inflammatory effects and as a tonic in Turkey. In this study, phenolic composition and anti-inflammatory activities of aerial part extract of <em>P. recta</em> from Turkey was examined. The chemical composition was analyzed <em>via </em>spectrophotometric and chromatographic (LC-MS/MS) techniques. The anti-inflammatory activity was determined by measuring the inhibitory effects on nitric oxide (NO) production and determining the levels of tumor necrosis factor alpha (TNF-α), interleukin-1 beta (IL-1β), interleukin-6 (IL-6) and interleukin-10 (IL-10) in lipopolysaccharide (LPS) stimulated RAW 264.7 cells. <em>P. recta</em> extract decreased the TNF-α level significantly compared to LPS group (2045.18±476.12 pg/mL). Potentillin was identified in the extract and the extract was found to be rich in phenolic compounds. These findings support the traditional use of <em>P. recta </em>with its strong anti-inflammatory activities. |
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| Date |
2018-09-14T07:22:41Z
2018-09-14T07:22:41Z 2018-10 |
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| Type |
Article
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| Identifier |
0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/45065 |
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| Language |
en_US
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| Relation |
<strong>Int. Cl.<sup>8</sup></strong>: A61K 36/00, A61K 9/00, A61K 38/00, A61K 39/395, A61K 45/06, A61K 36/73, A61K 31/56, A61K 31/7028, A61K 31/7032, A61K 31/7034
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJTK Vol.17(4) [October 2018]
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