Dielectric behaviour of neutrophil gelatinase associated lipocalin detected by alpha relaxation process
IR@NPL: CSIR-National Physical Laboratory, New Delhi
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Title |
Dielectric behaviour of neutrophil gelatinase associated lipocalin detected by alpha relaxation process
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Creator |
Tyagi, Mukta
Choudhary, Amit Upadhyay, Santosh K. Agrawal, Ved V. Biradar, A. M. |
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Subject |
Electronics and Electrical Engineering
Applied Physics/Condensed Matter |
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Description |
We have investigated alpha () relaxation process and its temperature evolution in electrical double layer (EDL) around neutrophil gelatinase-associated lipocalin (NGAL), anti-lipocalin2 (anti-LCN-2) and their conjugate in phosphate buffer. The dielectric permittivity (20Hz to 1MHz) of -relaxation process for LCN-2 and anti-LCN-2 shows variation with temperature. This happens due to unfolding of various microstates of protein at measured temperature intervals. The DSC thermograms of LCN-2, anti-LCN-2 and their conjugate predict that the multiple unfolding domains are parallel to the shifts in real dielectric permittivity at a particular temperature.
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Publisher |
Taylor & Francis
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Date |
2017
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://npl.csircentral.net/2659/1/Dielectric%20behaviour%20of%20neutrophil.pdf
Tyagi, Mukta and Choudhary, Amit and Upadhyay, Santosh K. and Agrawal, Ved V. and Biradar, A. M. (2017) Dielectric behaviour of neutrophil gelatinase associated lipocalin detected by alpha relaxation process. Integrated Ferroelectrics, 184 (1). pp. 55-68. ISSN 1058-4587 |
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Relation |
http://npl.csircentral.net/2659/
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