Interleukin-6 in impaired fasting glucose
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Interleukin-6 in impaired fasting glucose
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| Creator |
Agarwal, Ashish
Hegde, Anupama Yadav, Charu Ahmad, Afzal Manjrekar, Poornima A Rukmini, MS |
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| Subject |
Cardiovascular disease risk
Inflammation Prediabetes Insulin resistance Interleukin-6 |
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| Description |
424-428
Prediabetes is associated with the features of metabolic syndrome and inflammation contributing directly to the pathogenesis of cardiovascular disease (CVD). This study was conducted to explore the utility of interleukin-6 (IL-6) in determining the risk of CVD in prediabetes. It involves estimation of IL-6 & insulin along with its correlation with insulin, fasting plasma glucose (FPG), Insulin resistance (IR) and physical measurements. Eighty subjects were grouped into 40 prediabetes and 40 normoglycemic on the basis of FPG values. The mean insulin, IL-6, Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) and anthropometric measurements were found to be significantly higher (<em>P <</em>0.05) in prediabetes group. IL-6 had a significant correlation with fasting insulin (r = −0.413) and HOMA-IR (r = −0.413), but no correlation with FPG (r = −0.227) in the prediabetes group. IL-6 also showed a positive correlation with body mass index BMI(r = −0.339), waist circumference WC (r = −484) and waist-to-hip ratio WHR (r = −0.430). This study concludes that prediabetes is associated with inflammation, increasing the risk of CVD in these individuals. |
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| Date |
2018-11-29T05:28:03Z
2018-11-29T05:28:03Z 2018-12 |
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| Type |
Article
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| Identifier |
0975-0959 (Online); 0301-1208 (Print)
http://nopr.niscair.res.in/handle/123456789/45451 |
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| Language |
en_US
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJBB Vol.55(6) [December 2018]
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