Methylene Blue-Fortified Molybdenum Trioxide Nanoparticles: Harnessing Radical Scavenging Property
IR@CECRI: CSIR-Central Electrochemical Research Institute, Karaikudi
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Title |
Methylene Blue-Fortified Molybdenum Trioxide Nanoparticles: Harnessing Radical Scavenging Property
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Creator |
Marimuthu, M.
Praveen Kumar, B. Mariya Salomi, L. Veerapandian, M. Balamurugan, K. |
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Subject |
Functional Materials
Nanotechnology |
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Description |
A hybrid nanosystem with impeccable cellular imaging and antioxidant functionality is demonstrated. The microwave irradiation-derived molybdenum trioxide nanoparticles (MoO3 NPs) were surface-functionalized with the cationic
dye molecule, methylene blue (MB), which enables superior UV−visible absorbance and fluorescence emission wavelengths potential for bioimaging. The radical scavenging property of the pristine MoO3 NPs and MoO3−MB NPs were studied in vivo using Caenorhabditis elegans as the model system. Heat shock-induced oxidative stress in C. elegans was significantly resolved by the MoO3−MB NPs, in agreement with the in vitro radical scavenging study by electron paramagnetic resonance spectroscopy. Hybrid nanostructures of MoO3−MB demonstrate synergistic benefits in intracellular imaging with intrinsic biocompatibility and antioxidant behavior, which can facilitate application as advanced healthcare materials toward bioimaging and clinical therapeutics.
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Publisher |
ACS Publications
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Date |
2018-11-27
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Type |
Article
PeerReviewed |
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Format |
application/pdf
application/pdf |
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Identifier |
http://cecri.csircentral.net/3207/1/M.%20Marimuthu%20et%20al%202018.pdf
http://cecri.csircentral.net/3207/2/acsami.8b15841 Marimuthu, M. and Praveen Kumar, B. and Mariya Salomi, L. and Veerapandian, M. and Balamurugan, K. (2018) Methylene Blue-Fortified Molybdenum Trioxide Nanoparticles: Harnessing Radical Scavenging Property. ACS Applied Materials & Interfaces, 10 (50). pp. 43429-43438. ISSN 1944-8244 |
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Relation |
https://pubs.acs.org/page/aamick/about.html
http://cecri.csircentral.net/3207/ |
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