Triethylammonium acetate ionic liquid assisted one-pot synthesis of dihydropyrimidinones and evaluation of their antioxidant and antibacterial activities
IR@NPL: CSIR-National Physical Laboratory, New Delhi
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| Title |
Triethylammonium acetate ionic liquid assisted one-pot synthesis of dihydropyrimidinones and evaluation of their antioxidant and antibacterial activities
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| Creator |
Attri, Pankaj
Bhatia, Rohit Gaur, Jitender Arora, Bharti Gupta, Anjali Kumar, Naresh Choi, Eun Ha |
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| Subject |
Chemistry
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| Description |
A mild and efficient catalytic method has been developed to synthesize 3,4-dihydropyrimidinones in high yield by one-pot three component Biginelli condensation in the presence of triethylammonium acetate (TEAA) which acts as catalyst/reaction medium. Further, we have studied the antioxidant and antibacterial activities of these synthesized 3,4-dihydropyrimidinones. All the synthesized compounds reveal the significant antioxidant properties, these properties have been studied using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging and cupric reducing antioxidant capacity (CUPRAC) assays. In addition, to this, these compounds also show the good antibacterial activity against four human pathogenic bacteria. (C) 2014 King Saud University.
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| Publisher |
Elsevier
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| Date |
2017-02
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://npl.csircentral.net/2917/1/Triethylammonium%20acetate%20ionic%20liquid%20assisted%20one-pot%20synthesis%20of%20dihydropyrimidinones%20and%20evaluation%20of%20their%20antioxidant%20and%20antibacterial%20activities.pdf
Attri, Pankaj and Bhatia, Rohit and Gaur, Jitender and Arora, Bharti and Gupta, Anjali and Kumar, Naresh and Choi, Eun Ha (2017) Triethylammonium acetate ionic liquid assisted one-pot synthesis of dihydropyrimidinones and evaluation of their antioxidant and antibacterial activities. Arabian Journal of Chemistry, 10 (2). pp. 206-214. ISSN 1878-5352 |
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| Relation |
http://npl.csircentral.net/2917/
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