Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information.
IR@IMTECH: CSIR-Institute of Microbial Technology, Chandigarh
View Archive Info| Field | Value | |
| Title |
Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information.
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| Creator |
Panwar, Bharat
Gupta, Sudheer Raghava, G.P.S. |
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| Subject |
QR Microbiology
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| Description |
The vitamins are important cofactors in various enzymatic-reactions. In past, many inhibitors have been designed against vitamin binding pockets in order to inhibit vitamin-protein interactions. Thus, it is important to identify vitamin interacting residues in a protein. It is possible to detect vitamin-binding pockets on a protein, if its tertiary structure is known. Unfortunately tertiary structures of limited proteins are available. Therefore, it is important to develop in-silico models for predicting vitamin interacting residues in protein from its primary structure.
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| Publisher |
BMC part of Springer Nature
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| Date |
2013-02-07
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| Type |
Article
PeerReviewed |
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| Relation |
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-14-44
http://crdd.osdd.net/open/2449/ |
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| Identifier |
Panwar, Bharat and Gupta, Sudheer and Raghava, G.P.S. (2013) Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information. BMC bioinformatics, 14. p. 44. ISSN 1471-2105
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