Evolutionary insights into adaptation of Staphylococcus haemolyticus to human and non-human niches.
IR@IMTECH: CSIR-Institute of Microbial Technology, Chandigarh
View Archive Info| Field | Value | |
| Title |
Evolutionary insights into adaptation of Staphylococcus haemolyticus to human and non-human niches.
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| Creator |
Chaudhry, Vasvi
Patil, Prabhu B |
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| Subject |
QR Microbiology
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| Description |
Staphylococcus haemolyticus is a well-known member of human skin microbiome and an emerging opportunistic human pathogen. Presently, evolutionary studies are limited to human isolates even though it is reported from plants with beneficial properties and in environmental settings. In the present study, we report isolation of novel S. haemolyticus strains from surface sterilized rice seeds and compare their genome to other isolates from diverse niches available in public domain. The study showed expanding nature of pan-genome and revealed set of genes with putative functions related to its adaptability. This is seen by presence of type II lanthipeptide cluster in rice isolates, metal homeostasis genes in an isolate from copper coin and gene encoding methicillin resistance in human isolates. The present study on differential genome dynamics and role of horizontal gene transfers has provided novel insights into capability for ecological diversification of a bacterium of significance to human health.
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| Publisher |
Elsevier Science
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| Date |
2019-11-27
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| Type |
Article
PeerReviewed |
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| Relation |
https://www.sciencedirect.com/science/article/pii/S0888754319308043?via%3Dihub
http://crdd.osdd.net/open/2474/ |
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| Identifier |
Chaudhry, Vasvi and Patil, Prabhu B (2019) Evolutionary insights into adaptation of Staphylococcus haemolyticus to human and non-human niches. Genomics. ISSN 1089-8646 (In Press)
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