An emerging nanostructured molybdenum trioxide based biocompatible sensor platform for breast cancer biomarker detection
IR@NPL: CSIR-National Physical Laboratory, New Delhi
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Title |
An emerging nanostructured molybdenum trioxide based biocompatible sensor platform for breast cancer biomarker detection
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Creator |
Augustine, Shine
Joshi, Amish G. Yadav, Birendra Kumar Mehta, Anurag Kumar, Preget Renugopalakrishanan, Venkatesan Malhotra, Bansi D. |
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Subject |
Materials Science
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Description |
We report results of the studies relating to the development of the emerging nanostructured molybdenum trioxide (nMoO(3))-based biocompatible label-free biosensing platform for breast cancer detection. The structural and morphological studies of the synthesized nMoO(3) nano-rods were investigated by XRD, SEM, X-ray photoelectron spectroscopic. and TEM techniques. This biocompatible one-dimensional (1D) nMoO(3)-based biosensing platform exhibited high sensitivity (0.904 mu AmUng/cm(2)). wide linear detection range (2.5-110 ng/mL), and a lower detection limit as 2.47 ng/mL toward human epidermal growth factor receptor-2 detection. The results obtained using this sensor platform on serum samples of breast cancer patients were validated using ELISA.
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Publisher |
Institute of Electrical and Electronics Engineers
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Date |
2018-09
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://npl.csircentral.net/4076/1/An%20emerging%20nanostructured.pdf
Augustine, Shine and Joshi, Amish G. and Yadav, Birendra Kumar and Mehta, Anurag and Kumar, Preget and Renugopalakrishanan, Venkatesan and Malhotra, Bansi D. (2018) An emerging nanostructured molybdenum trioxide based biocompatible sensor platform for breast cancer biomarker detection. Proceedings of IEEE Sensors, 8 (3). pp. 668-679. ISSN 2159-6859 |
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Relation |
http://npl.csircentral.net/4076/
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