Electrophoretically fabricated core-shell CNT-DNA biowires for biosensing
IR@NPL: CSIR-National Physical Laboratory, New Delhi
View Archive Info| Field | Value | |
| Title |
Electrophoretically fabricated core-shell CNT-DNA biowires for biosensing
|
|
| Creator |
Das, Maumita
Dhand, Chetna Sumana, Gajjala Srivastava, Avanish Kumar Nagarajan, Rajamani Malhotra, Bansi Dhar |
|
| Subject |
Materials Science
Physical Chemistry/Chemical Physics |
|
| Description |
In view of recent revelations and potential applications of the carbon nanotubes (CNT)-deoxyribonucleic acid (DNA) nanobiohybrids, we propose a mechanism of DNA wrapping onto functionalized CNT using principles of co-ordination chemistry. The core-shell structural biowire comprising of CNT and DNA has been fabricated via electrophoretic deposition technique and detailed morphological investigations have been carried out to ascertain the mechanism of biowire formation. The results of these studies reveal that during the biowire formation, Mg2+ ions provide the central metal ion with enhanced structural and catalytic activity for DNA and CNT to covalently co-ordinate to form a bi-cyclic chelate structure. Employing the synergy between the nanomaterial and biomolecule, DNA-Mg2+-CNT biowires can be used as a nanobioelectrode platform for development of a genosensor.
|
|
| Publisher |
Royal Society of Chemistry
|
|
| Date |
2012
|
|
| Type |
Article
PeerReviewed |
|
| Format |
application/pdf
|
|
| Identifier |
http://npl.csircentral.net/3592/1/Electrophoretically%20fabricated.pdf
Das, Maumita and Dhand, Chetna and Sumana, Gajjala and Srivastava, Avanish Kumar and Nagarajan, Rajamani and Malhotra, Bansi Dhar (2012) Electrophoretically fabricated core-shell CNT-DNA biowires for biosensing. Journal of Materials Chemistry , 22 (6). pp. 2727-2732. ISSN 0959-9428 |
|
| Relation |
http://npl.csircentral.net/3592/
|
|