1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU): as a highly efficient bicyclic amidine catalyst promoted solvent-free and one-pot synthesis of 1H-pyrazolo [1, 2-b] phthalazine-5,10-dione derivatives
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
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| Title |
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU): as a highly efficient bicyclic amidine catalyst promoted solvent-free and one-pot synthesis of 1H-pyrazolo [1, 2-b] phthalazine-5,10-dione derivatives
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| Creator |
Mohamadpour, Farzaneh
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| Subject |
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)
Highly efficient bicyclic amidine catalyst 1H-pyrazolo [1, 2-b] phthalazine-5 10-dione derivatives Solvent-free conditions One-pot procedure |
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| Description |
1234-1242
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) as a highly efficient bicyclic amidine catalyst promoted one-pot multi-component synthesis of biologically active 1<em>H</em>-pyrazolo [1, 2-b] phthalazine-5, 10-dione derivatives <em>via</em> one-pot four-component condensation reaction of phthalimide, hydrazine monohydrate, aryl aldehydes and malononitrile under solvent-free conditions through simple filter with no necessity of chromatographic purification steps. Use of safe, non-volatile, non-corrosive, highly efficient, readily available and easy to handle of catalyst, one-pot reaction, high yields and short reaction times, economical and convenient synthesis, solvent-free conditions and operational simplicity are among the other added advantages that make this approach an attractive alternative for the synthesis of these biologically active compounds. |
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| Date |
2020-10-05T08:22:31Z
2020-10-05T08:22:31Z 2020-08 |
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| Type |
Article
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/55433 |
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| Language |
en_US
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJC-B Vol.59B(08) [August 2020]
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