Bioprospecting of the underutilized endemic taxon Cissus woodrowii (Stapf ex Cooke) Santapau for its antioxidant activity and phenolic profiling
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Bioprospecting of the underutilized endemic taxon Cissus woodrowii (Stapf ex Cooke) Santapau for its antioxidant activity and phenolic profiling
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| Creator |
Kolap, Rupali Mukesh
Gulave, Akshay Bharat Zimare, Saurabha Bhimrao |
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| Subject |
Antioxidant activity
Cissus woodrowii HPLC LC-HRMS Phenolic profiling Woodrow’s grape tree |
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| Description |
250-259
The present study explored the antioxidant potential of endemic <em>Cissus woodrowii </em>(CW) which is an underutilised tree taxon of the Vitaceae family. Maximum per cent yield (13.49%), total phenolic content (24.14 mg TAE/g dry weight), and total flavonoid content (18.45 mg QE/g dry weight) were recorded in the methanolic leaf extract. Whereas the <em>in vitro</em> antioxidant activities of different extracts were assessed using 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid), 2,2-diphenyl-1-picrylhydrazyl, hydroxyl, nitric oxide, hydrogen peroxide percent radical scavenging activity (% RSA), antioxidant power assay (ferric-reducing antioxidant power), and total antioxidant capacity (phosphomolybdate assay). Antioxidant activity of CW extract may be due to its high level of phenolic compounds, which were screened through liquid chromatography–high-resolution mass spectrometry (LC-HRMS), and the selected three phenolic compounds were quantified using high-performance liquid chromatography (HPLC). The HPLC analysis revealed a higher concentration of gallic acid (119.78 µg/g dry weight), followed by quercetin (22.13 µg/g dry weight) and embelin (21.09 µg/g dry weight). This is the first report on this underexplored taxon which could be employed for the development of several nutraceuticals and pharmaceuticals. |
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| Date |
2021-02-04T09:23:42Z
2021-02-04T09:23:42Z 2020-12 |
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| Type |
Article
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| Identifier |
0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/56147 |
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| Language |
en_US
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| Relation |
Int. cl. (2015.01)− A61K 36/00, A61K 36/87, A61K 127/00, A61P 39/00
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJNPR Vol.11(4) [December 2020]
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