Antioxidant and antitubercular activities of leaf extracts of Canthium dicoccum (Gaertn.) and Amischophacelus axillaris (L.)
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Antioxidant and antitubercular activities of leaf extracts of Canthium dicoccum (Gaertn.) and Amischophacelus axillaris (L.)
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| Creator |
Meghashree, K. S.
Latha, K. P. Vagdevi, H. M. |
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| Subject |
Amischophacelus axillaris (L.)
Antioxidant Antitubercular Canthium dicoccum (Gaertn.) Ethanol extract Ethyl acetate extract |
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| Description |
244-249
Modern civilization is facing hundreds of disorders associated with free radicals. The natural antioxidants from <br /> non-edible plants are gaining importance to fight against these disorders. One such commonly seen disorder is tuberculosis, which is responsible for about 8 million deaths annually worldwide. This study intends to evaluate the ethanol extracts of <em>Canthium dicoccum </em>(Gaertn.) and ethyl acetate extracts of <em>Amischophacelus axillaris </em>(L.) for antioxidant and antitubercular activities. The antioxidant activity of the extracts has been evaluated using DPPH radical scavenging methods. The results of the study indicated that ethanol extract of <em>C. dicoccum </em>(Gaertn.) and ethyl acetate extract of <em>A. axillaris</em> (L.) possess promising DPPH radical scavenging activity. The antitubercular activity of ethanol extract of <em>C. dicoccum </em>(Gaertn.) and ethyl acetate extract of<em> A. axillaris </em>(L.) have been evaluated against <em>Mycobacterium tuberculosis</em> H73Rv strain using Microplate Alamar Blue Assay (MABA). The activity was documented within the MIC range of 0.8 to 12.5 µg/mL for <em>C. dicoccum </em>(Gaertn.) and 0.8 to 50 µg/mL for <em>A. axillaris </em>(L.). The results of MABA showed that both the plant extracts exhibited excellent antitubercular activity. The present investigation suggests that <em>C. dicoccum </em>(Gaertn.) and <em>A. axillaris </em>(L.) possess remarkable antioxidant and antitubercular activity. |
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| Date |
2021-02-04T09:28:33Z
2021-02-04T09:28:33Z 2020-12 |
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| Type |
Article
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| Identifier |
0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/56148 |
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| Language |
en_US
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| Relation |
Int. cl. (2015.01)- A61K 36/00, A61K 36/74, A61K 127/00, A61P 31/00, A61P 31/06, A61P 39/00
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJNPR Vol.11(4) [December 2020]
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