Enantiospecific total synthesis of ent-10,11-thapsan-10-ol
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Creator |
Srikrishna, A
Anebouselvy, K |
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| Date |
2009-03-25T04:01:30Z
2009-03-25T04:01:30Z 2009 |
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| Identifier |
0376-4699
http://hdl.handle.net/123456789/3464 |
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| Description |
413-422
First enantiospecific total synthesis of optical antipode of the sesquiterpene 10,11-epoxythapsan-10-ol has been described. (R)-Carvone has been employed as the chiral starting material and a combination of intramolecular alkylation and Criegee fragmentation are employed for intramolecular stereospecific transfer of the chirality. An intramolecular diazoketone cyclopropanation and regioselective cyclopropane ring cleavage reactions have been employed for the creation of the three requisite contiguous quaternary carbon atoms. |
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| Language |
en_US
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| Publisher |
CSIR
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| Source |
IJC-B Vol.48B(03) [March 2009]
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| Subject |
Enantiospecific
Thapsia garganica thapsane Thapsia villosa |
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| Title |
Enantiospecific total synthesis of ent-10,11-thapsan-10-ol
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| Type |
Article
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