<b style="">Evaluation of the antipyretic potential of methanol extract of the leaves of </b> <b style=""><i style="">Abies</i></b><b style=""><i style=""> spectabilis </i>(D. Don) Spach.</b><b style=""></b>
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Creator |
Visnoi, Satya Prakash
Basu, Anindya Alam, S k Mahasin Samanta, Soma Jha, Tarun |
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| Date |
2010-04-08T05:07:50Z
2010-04-08T05:07:50Z 2007-10 |
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| Identifier |
0975-1092 (Online); 0972-592X (Print)
http://hdl.handle.net/123456789/7885 |
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| Description |
369-371
Methanol extract of leaves of <b style=""><i style="">Abies</i></b><b style=""><i style=""> spectabilis </i>(D. Don) Spach.</b><b style=""> </b>(MEAS) was evaluated for the antipyretic potential on normal body temperature and yeast induced pyrexia in rats. MEAS showed significant activity at intraperitonial (i.p.) doses of 200 and 400mg/kg body weight. The extract, when administered at a dose of 200mg/kg body weight caused significant lowering of body temperature up to 3h. With 400 mg/kg body weight dose it caused significant lowering of body temperature up to 6h after administration. In the model of yeast induced elevation of body temperature MEAS showed dose-dependant lowering of the body temperature up to 4h at both the doses. The results obtained, were comparable to that of paracetamol, a standard antipyretic agent. |
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| Language |
en_US
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| Publisher |
CSIR
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| Relation |
<b>Int. cl.<sup>8</sup>— </b>A61K 36/00, A61K 36/15, A61K 127/00, A61P 29/00 <b> </b>
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| Source |
NPR Vol.6(5) [September-October 2007]
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| Subject |
<i style="">Abies</i><b style=""><i style=""> </i></b><i style="">spectabilis</i>
Antipyretic Methanol extract Yeast-induced pyrexia |
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| Title |
<b style="">Evaluation of the antipyretic potential of methanol extract of the leaves of </b> <b style=""><i style="">Abies</i></b><b style=""><i style=""> spectabilis </i>(D. Don) Spach.</b><b style=""></b>
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| Type |
Article
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