2-Amino-5-sulphanyl-1,3,4-thiadiazole derivatives as anticonvulsant agents: Synthesis and evaluation <strong>[RETRACTED ARTICLE]</strong>
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Creator |
Pattanayak, Priyabrata
Sharma, Rajesh |
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| Date |
2010-11-08T10:46:26Z
2010-11-08T10:46:26Z 2010-11 |
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/10541 |
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| Description |
1531-1534
A series of 2-amino-5-sulphanyl-1,3,4-thiadiazole derivatives bearing different substituents have been synthesized and screened in order to evaluate for their central nervous system activity. Anticonvulsant activity of the title compounds has been evaluated by varying the substituents in the thiadiazole moiety. The newly synthesized intermediates and compounds have been characterized by spectral analysis. Two of the tested compounds <b style="">3a</b> and <b style="">3b</b> have been found to exhibit excellent anticonvulsant activity in comparison to the reference drugs in both the pharmacological models. |
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| Language |
en_US
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| Publisher |
NISCAIR-CSIR, India
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Source |
IJC-B Vol.49B(11) [November 2010]
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| Subject |
Maximal electroshock
PTZ animal model thiadiazoles |
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| Title |
2-Amino-5-sulphanyl-1,3,4-thiadiazole derivatives as anticonvulsant agents: Synthesis and evaluation <strong>[RETRACTED ARTICLE]</strong>
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| Type |
Article
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