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Field Value
 
Creator George, SC
John, J
Anas, S
John, J
Yamamoto, Y
Suresh, E
Radhakrishnan, KV
 
Subject Chemistry
 
Description An effective protocol has been developed for the construction of 3,3-disubstituted indol-2-ones from isatylidenes by utilizing amphiphilic bis-pi-allylpalladium and related intermediates. The developed strategy is a new method for the quaternization of position 3 of the indol-2-one towards disubstituted functionalized indol-2-ones. These products were subjected to ring-closing metathesis towards the synthesis of spiro[cyclohexene-1,3 '-indol]-2 '-ones and spiro[oxep-5-ene-2,3 '-indol]-2 '-ones, which are of biological interest.
 
Publisher WILEY-BLACKWELLMALDENCOMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
 
Date 2011-09-20T12:03:10Z
2011-09-20T12:03:10Z
2010
 
Type Article
 
Identifier EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
1434-193X
http://hdl.handle.net/123456789/12204
 
Language English