Metadata of CSIR Papers
View Archive Info| Field | Value | |
| Creator |
Khan, NUH
Saravanan, S Kureshy, RI Abdi, SHR Bajaj, HC |
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| Subject |
Chemistry
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| Description |
Chiral monomeric and dimeric Mn(III) salen complexes viz., [(S,S)-N,N'-bis(3,5-di-tert-butylsalicylidene)1,2-cyclohexanediaminato manganese(III) chloride and 5,5-methylene di-[(S,S)-[N-(3-tert-butyl salicylidene))-1,2-cyclohexanediaminato manganese(Ill) chloride were used as catalysts for the highly enantioselective Strecker reaction of various imines (derived by the condensation of aldehydes and amine) with TMSCN as a source of cyanide in toluene. Excellent yield (95%) of a-amino nitrile with ee >99% was achieved when N-(2-methoxybenzylidine)-1-phenylmethanamine was used as a substrate and 4-phenyl pyridine-N-oxide (4-PPNO) as an additive at 55 degrees C in 28 h. The dimeric catalyst was found to be more reactive and enantioselective than the monomeric catalyst. The chiral dimeric catalyst used in the present study was recoverable and recyclable several times with retention of its performance. (C) 2010 Elsevier Ltd. All rights reserved.
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| Publisher |
PERGAMON-ELSEVIER SCIENCE LTDOXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
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| Date |
2011-09-20T12:03:11Z
2011-09-20T12:03:11Z 2010 |
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| Type |
Article
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| Identifier |
TETRAHEDRON-ASYMMETRY
0957-4166 http://hdl.handle.net/123456789/12211 |
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| Language |
English
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