Metadata of CSIR Papers
View Archive Info| Field | Value | |
| Creator |
Khan, NUH
Agrawal, S Kureshy, RI Abdi, SHR Pathak, K Bajaj, HC |
|
| Subject |
Pharmacology & Pharmacy; Chemistry
|
|
| Description |
Polymeric and monomeric V(V) chiral salen complexes-catalyzed enantioselective ethyl cyanoformylation of aldehydes using ethyl cyanoformate as a source of cyanide was accomplished in the presence of several basic cocatalysts viz., NaOH, KOH, basic Al(2)O(3) and hydrotalcite. Excellent yield (>95%) of chiral ethyl cyanohydrincarbonate with high enantioselectivity up to 94% was achieved in 24-36 h when hydrotalcite was used as an additive. The polymeric catalyst 1 is more reactive than the monomeric catalyst 2 to produce chiral ethyl cyanohydrincarbonate in high optical purity. The chiral polymeric catalyst 1 and cocatalysts hydrotalcite and basic alumina used in this study were recoverable and recyclable several times with retention of its performance. Chirality 22:153-158, 2010. (C) 2009 Wiley-Liss, Inc.
|
|
| Publisher |
WILEY-LISSHOBOKENDIV JOHN WILEY & SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 USA
|
|
| Date |
2011-09-20T12:03:28Z
2011-09-20T12:03:28Z 2010 |
|
| Type |
Article
|
|
| Identifier |
CHIRALITY
0899-0042 http://hdl.handle.net/123456789/12346 |
|
| Language |
English
|
|