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Field Value
 
Creator Kumar, J
Garg, G
Karthikeyan, G
Sengupta, S
 
Subject Biotechnology & Applied Microbiology; Toxicology
 
Description Cystathionine beta-synthase (CBS) is a key enzyme that plays a critical role in homocysteine metabolism and intracellular redox balance. We have analysed the association of the CBS 844Ins68 polymorphism alone and in combination with methylenetetrahydrofolate reductase (MTHFR C677T) and choline dehydrogenase (CHDH A119C) polymorphisms (the two polymorphisms recently shown to be associated with levels of homocysteine) with homocysteine, cysteine, folate and vitamin B(12) in 817 individuals (397 patients with coronary artery disease and 420 controls). The CBS 844Ins68 polymorphism alone or in combination with MTHFR C677T and CHDH A119C polymorphisms was not significantly associated with any of the biochemical variables studied.</.
 
Publisher TAYLOR & FRANCIS LTDABINGDON4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
 
Date 2011-09-20T12:07:10Z
2011-09-20T12:07:10Z
2010
 
Type Article
 
Identifier BIOMARKERS
1354-750X
http://hdl.handle.net/123456789/13132
 
Language English