Metadata of CSIR Papers
View Archive InfoField | Value | |
Creator |
Kumar, J
Garg, G Karthikeyan, G Sengupta, S |
|
Subject |
Biotechnology & Applied Microbiology; Toxicology
|
|
Description |
Cystathionine beta-synthase (CBS) is a key enzyme that plays a critical role in homocysteine metabolism and intracellular redox balance. We have analysed the association of the CBS 844Ins68 polymorphism alone and in combination with methylenetetrahydrofolate reductase (MTHFR C677T) and choline dehydrogenase (CHDH A119C) polymorphisms (the two polymorphisms recently shown to be associated with levels of homocysteine) with homocysteine, cysteine, folate and vitamin B(12) in 817 individuals (397 patients with coronary artery disease and 420 controls). The CBS 844Ins68 polymorphism alone or in combination with MTHFR C677T and CHDH A119C polymorphisms was not significantly associated with any of the biochemical variables studied.</.
|
|
Publisher |
TAYLOR & FRANCIS LTDABINGDON4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
|
|
Date |
2011-09-20T12:07:10Z
2011-09-20T12:07:10Z 2010 |
|
Type |
Article
|
|
Identifier |
BIOMARKERS
1354-750X http://hdl.handle.net/123456789/13132 |
|
Language |
English
|
|