Protective role of S-adenosyl-L-methionine against hydrochloric acid stress in Saccharomyces cerevisiae
Metadata of CSIR Papers
View Archive Info| Field | Value | |
| Title |
Protective role of S-adenosyl-L-methionine against hydrochloric acid stress in Saccharomyces cerevisiae
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| Creator |
Malakar, D
Dey, A Ghosh, AK |
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| Subject |
Biochemistry & Molecular Biology; Biophysics
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| Description |
S-adenoSyl-L-methionine (AdoMet, 1 mM) protects the stationary phase cells of Saccharomyces cerevisiae against the killing effect of acid (10 mM HCl, pH similar to 2). Both the acid and the acid plus AdoMet treatment for 2 h increased the plasma membrane H+-ATPase activity; thereafter it decreased to the basal level. AdoMet partially recovered the intracellular pH (pH(in)) that dropped in presence of acid. AdoMet treatment facilitated acid induced phospholipid biosynthesis as well as membrane proliferation, which was reflected in the cellular lipid composition. (c) 2006 Elsevier B.V All rights reserved.
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| Publisher |
ELSEVIER SCIENCE BVAMSTERDAMPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
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| Date |
2011-09-20T12:12:06Z
2011-09-20T12:12:06Z 2006 |
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| Type |
Article
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| Identifier |
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
0304-4165 http://hdl.handle.net/123456789/14124 |
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| Language |
English
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