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Peroxisome is a reservoir of intracellular calcium

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Title Peroxisome is a reservoir of intracellular calcium
 
Creator Raychaudhury, B
Gupta, S
Banerjee, S
Datta, SC
 
Subject Biochemistry & Molecular Biology; Biophysics
 
Description We have examined fura 2-loaded purified peroxisomes under confocal microscope to prove that this mammalian organelle is a store of intracellular calcium pool. Presence of calcium channel and vanadate sensitive Ca2+-ATPase in the purified peroxisomal membrane has been demonstrated. We have further observed that machineries to maintain calcium pool in this mammalian organelle are impaired during infection caused by Leishmania donovani. Results reveal that peroxisomes have a merit to play a significant role in the metabolism of intracellular calcium. (c) 2006 Elsevier B.V. All rights reserved.
 
Publisher ELSEVIER SCIENCE BVAMSTERDAMPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
 
Date 2011-09-20T12:12:11Z
2011-09-20T12:12:11Z
2006
 
Type Article
 
Identifier BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
0304-4165
http://hdl.handle.net/123456789/14163
 
Language English