Glycobiology of Leishmania donovani
Metadata of CSIR Papers
View Archive Info| Field | Value | |
| Title |
Glycobiology of Leishmania donovani
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| Creator |
Mukhopadhyay, S
Mandal, C |
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| Subject |
Immunology; Medicine, General & Internal; Medicine, Research & Experimental
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| Description |
Leishmania donovani, the causative organism of visceral leishmaniasis (VL) is one of the deadliest of the entire known Leishmania species. This protozoan parasite displays immense adaptability to survive under extremely harsh conditions. Cell surface glycoconjugates play a pivotal role in parasite virulence and infectivity. This review mainly highlights on the importance of these molecules and their reported roles with special emphasis on L. donovani sialobiology. The recently evolved information reported by our group regarding the identification and characterization of sialoglycans and their possible mode(s) of acquisition as also the detailed identification, characterization of anti-O-acetylated sialic acid (anti-OAcSA) antibodies and their emerging biological roles, notably as molecules that may aid in host defense against the pathogen has been vividly discussed in this review.
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| Publisher |
INDIAN COUNCIL MEDICAL RESNEW DELHIPO BOX 4911 ANSARI NAGAR, NEW DELHI 110029, INDIA
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| Date |
2011-09-20T12:12:13Z
2011-09-20T12:12:13Z 2006 |
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| Type |
Review
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| Identifier |
INDIAN JOURNAL OF MEDICAL RESEARCH
0971-5916 http://hdl.handle.net/123456789/14180 |
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| Language |
English
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