Involvement of novel PKC isoforms in FFA induced defects in insulin signaling
Metadata of CSIR Papers
View Archive Info| Field | Value | |
| Title |
Involvement of novel PKC isoforms in FFA induced defects in insulin signaling
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| Creator |
Dey, D
Basu, D Roy, SS Bandyopadhyay, A Bhattacharya, S |
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| Subject |
Cell Biology; Endocrinology & Metabolism
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| Description |
Involvement of novel PKCs (nPKCs) in the negative regulation of insulin-signaling pathway is a current interest of many workers investigating the cause for insulin resistance and type 2 diabetes. Free fatty acids (FFAs) are recently shown to be the major players in inducing insulin resistance in insulin target cells. They are also found to be involved in activating nPKCs associated with the impairment of insulin sensitivity. In this overview, we describe PKC delta, theta and epsilon linked to the FFA induced damage of insulin-signaling molecules. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
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| Publisher |
ELSEVIER IRELAND LTDCLAREELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND
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| Date |
2011-09-20T12:12:19Z
2011-09-20T12:12:19Z 2006 |
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| Type |
Proceedings Paper
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| Identifier |
MOLECULAR AND CELLULAR ENDOCRINOLOGY
0303-7207 http://hdl.handle.net/123456789/14220 |
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| Language |
English
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