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A triterpenoid saponin possessing antileishmanial activity from the leaves of Careya arborea

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Title A triterpenoid saponin possessing antileishmanial activity from the leaves of Careya arborea
 
Creator Mandal, D
Panda, N
Kumar, S
Banerjee, S
Mandal, NB
Sahu, NP
 
Subject Biochemistry & Molecular Biology; Plant Sciences
 
Description Bioguided-fractionation of the methanol extract of the leaves of Careya arborea led to isolation of a triterpenoid saponin, designated arborenin, and characterized as 3-O-beta-D-glucopyranosyl(1 -> 2)-beta-D-glueopyranosyl-2 alpha,3 beta-dihydroxy-taraxast-20-en-28-oic acid (1), together with desacylescin 111 (2). The structures were determined on the basis of extensive 2D NMR spectroscopic analysis. The saponin showed in vitro antileishmanial activity against Leishmania donovani (strain AG 83). (c) 2005 Elsevier Ltd. All rights reserved.
 
Publisher PERGAMON-ELSEVIER SCIENCE LTDOXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
 
Date 2011-09-20T12:12:21Z
2011-09-20T12:12:21Z
2006
 
Type Article
 
Identifier PHYTOCHEMISTRY
0031-9422
http://hdl.handle.net/123456789/14237
 
Language English