Cell adhesion by aqueous extract of human placenta used as wound healer
Metadata of CSIR Papers
View Archive Info| Field | Value | |
| Title |
Cell adhesion by aqueous extract of human placenta used as wound healer
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| Creator |
Nath, S
Bhattacharyya, D |
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| Subject |
Biology
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| Description |
Aqueous extract of human placenta, used as wound healer, has shown significant cell adhesion property on mouse peritoneal macrophages and P-388D1 cultured macrophage cell line. This property was offered primarily by fibronectin type III like peptide present in the extract and is comparable to fibronectin on a molar basis. The peptide induce adhesion of cell through cell surface receptors having Kd = 2.8 +/- 0.9 x 10(-5) M suggesting weak binding. This is in support of integrins receptors that typically exhibit low affinities. Cell adhesion was partially inhibited by Arg-Gly-Asp (RGD) peptide, anti-P, integrin suggesting that integrin beta(1), receptors have roles to play in the process.
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| Publisher |
NATL INST SCIENCE COMMUNICATIONNEW DELHIDR K S KRISHNAN MARG, NEW DELHI 110 012, INDIA
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| Date |
2011-09-20T12:12:30Z
2011-09-20T12:12:30Z 2007 |
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| Type |
Article
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| Identifier |
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY
0019-5189 http://hdl.handle.net/123456789/14298 |
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| Language |
English
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