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Pyrrolidine nucleic acids: DNA/PNA oligomers with 2-hydroxy/aminomethyl-4-(thymin-1-yl)pyrrolidine-N-acetic acid

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Title Pyrrolidine nucleic acids: DNA/PNA oligomers with 2-hydroxy/aminomethyl-4-(thymin-1-yl)pyrrolidine-N-acetic acid
 
Creator Kumar, V
Pallan, PS
Meena
Ganesh, KN
 
Subject Chemistry, Organic
 
Description [GRAPHICS] Synthesis of pyrrolidine-based chiral positively charged DNA analogues is reported, The synthesis of (2S,4S) and (2R,4R) thymin-1-ylpyrrolidine-N-acetic acid, its site specific incorporation in PNA:DNA chimera and PNA, and the study of their binding properties with complementary DNA/RNA sequences is presented.
 
Publisher AMER CHEMICAL SOCWASHINGTON1155 16TH ST, NW, WASHINGTON, DC 20036 USA
 
Date 2011-09-24T08:45:39Z
2011-09-24T08:45:39Z
2001
 
Type Article
 
Identifier ORGANIC LETTERS
1523-7060
http://hdl.handle.net/123456789/24075
 
Language English