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Aminoethylprolyl (aep) PNA: Mixed purine/pyrimidine oligomers and binding orientation preferences for PNA : DNA duplex formation

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Title Aminoethylprolyl (aep) PNA: Mixed purine/pyrimidine oligomers and binding orientation preferences for PNA : DNA duplex formation
 
Creator D'Costa, M
Kumar, V
Ganesh, KN
 
Subject Chemistry, Organic
 
Description [GRAPHICS] The synthesis of (2S,4S)- and (PR,4S)-aepPNA monomers of adenine, guanine, and cytosine (3-5) end their incorporation at appropriate positions into aegPNA sequence 7 leads to mixed aeg-aep backbone/mixed nucleobase PNAs 8-11, The thermal stabilities of the derived duplexes with DNA are found to be dependent on nucleobase and backbone stereochemistry.
 
Publisher AMER CHEMICAL SOCWASHINGTON1155 16TH ST, NW, WASHINGTON, DC 20036 USA
 
Date 2011-09-24T08:46:09Z
2011-09-24T08:46:09Z
2001
 
Type Article
 
Identifier ORGANIC LETTERS
1523-7060
http://hdl.handle.net/123456789/24076
 
Language English