A facile synthesis of a (+/-)-2,3-disubstituted maleic anhydride segment of tautomycin
Metadata of CSIR Papers
View Archive Info| Field | Value | |
| Title |
A facile synthesis of a (+/-)-2,3-disubstituted maleic anhydride segment of tautomycin
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| Creator |
Deshpande, AM
Natu, AA Argade, NP |
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| Subject |
Chemistry, Organic
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| Description |
A convenient method for construction of a (+/-)-2,3-disubstituted maleic anhydride segment of antibiotic tautomycin is reported. The key steps involved in the synthesis are chemoselective condensation of diethyl malonate with 2-(bromomethyl)-3-methylmaleic anhydride (3) and regioselective NBS-bromination of the maleic anhydride derivative 7.
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| Publisher |
GEORG THIEME VERLAG KGSTUTTGARTRUDIGERSTR 14, D-70469 STUTTGART, GERMANY
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| Date |
2011-09-24T08:48:39Z
2011-09-24T08:48:39Z 2001 |
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| Type |
Article
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| Identifier |
SYNTHESIS-STUTTGART
0039-7881 http://hdl.handle.net/123456789/24081 |
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| Language |
English
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