Sulfonate protecting groups. Regioselective O-sulfonylation of myo-inositol orthoesters
Metadata of CSIR Papers
View Archive Info| Field | Value | |
| Title |
Sulfonate protecting groups. Regioselective O-sulfonylation of myo-inositol orthoesters
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| Creator |
Sureshan, KM
Shashidhar, MS |
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| Subject |
Chemistry, Organic
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| Description |
Sulfonylation of myo-inositol 1,3,5-orthoesters with alkyl or aryl sulfonyl chlorides in the presence of sodium hydride gives the corresponding 4,6-di-O-sulfonates in good yields. These sulfonates can be cleaved with magnesium in methanol to generate the free myo-inositol derivative. This methodology was used for the preparation of racemic 2,4-di-O-benzyl-myo-inositol and 2-O-benzyl-myo-inositol, which are precursors for some phosphoinositols. (C) 2001 Elsevier Science Ltd. All rights reserved.
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| Publisher |
PERGAMON-ELSEVIER SCIENCE LTDOXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
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| Date |
2011-09-24T08:53:40Z
2011-09-24T08:53:40Z 2001 |
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| Type |
Article
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| Identifier |
TETRAHEDRON LETTERS
0040-4039 http://hdl.handle.net/123456789/24091 |
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| Language |
English
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