Synthesis and antimicrobial studies of Schiff bases of fluoroquinolone
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Creator |
Patel, Navin B
Patel, Sarvil D Patel, Arvind L Patel, Jaymin C Patel, Jignesh N |
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| Date |
2011-11-03T11:18:36Z
2011-11-03T11:18:36Z 2011-11 |
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/13049 |
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| Description |
1645-1657
Series of Schiff bases of fluoroquinolone have been synthesized from lead molecule 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-chloro-3-quinolinecarbonyl chloride, converted to hydrazide and further reacted with substituted aldehydes and finally condensed with piperazines, morpholine, imidazole. The title compounds have been characterized by elemental analysis, IR, <sup>1</sup>H NMR spectra. All the synthesized compounds have been screened for their antimicrobial activity against five microbes. Majority of them exhibit moderate activity where as good activity has been observed for <i style="">S. </i>aureus. |
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| Language |
en_US
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| Publisher |
NISCAIR-CSIR, India
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Source |
IJC-B Vol.50B(11) [November 2011]
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| Subject |
Schiff base
Fluoroquinolone Antimicrobial |
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| Title |
Synthesis and antimicrobial studies of Schiff bases of fluoroquinolone
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| Type |
Article
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